Gliclanux M 80 Tablet is primarily utilised to manage type 2 diabetes mellitus in adults. This formulation is a combination of sulfonylureas and biguanides.
Gliclanux M 80 Tablet is prescribed for:
• Management of type 2 diabetes mellitus in adults
• Lowering elevated blood glucose levels
• Prevention of diabetes-related cardiovascular complications
• Protection against nerve damage due to chronic hyperglycaemia
• Prevention of diabetic nephropathy and retinopathy
• Take the this tablet whole with food.
• It should be taken at the same time every day for optimal efficacy.
• Do not chew or crush the tablet.
• Continue to take this medication as advised by your doctor, even if you feel well.
This tablet is taken orally.
The side effects of this tablet may include:
• Hypoglycaemia, characterised by symptoms such as shaking, sweating, and confusion
• Gastrointestinal disturbances including nausea, vomiting, or diarrhoea
• Flatulence
• Dizziness and headache
• Upper respiratory tract infections
Gliclanux M 80 Tablet comprises two active ingredients:
• Gliclazide (80 mg): This sulfonylurea promotes insulin secretion from pancreatic beta cells and enhances insulin sensitivity at peripheral sites, effectively lowering blood glucose levels.
• Metformin (500 mg): As a biguanide, metformin curtails hepatic glucose production and improves insulin sensitivity. It also delays intestinal glucose absorption and facilitates glucose uptake and utilisation by muscles.
Contraindicated.
Contraindicated.
Consuming alcohol may increase the risk of lactic acidosis or hypoglycaemia.
Contraindicated.
Contraindicated in severe renal impairment.
Exercise caution until you know how this tablet affects you.
Avoid this tablet if you have known allergies to gliclazide, metformin, or any other constituent of the tablet.
Not indicated for individuals under 18 years of age.
Decreased liver or kidney function can put older patients at higher risk of developing lactic acidosis.
Drug-Drug Interactions
• Other Anti-diabetic Medicines: Concomitant use with insulin or other oral anti-diabetics may elevate the risk of hypoglycaemia.
• Diuretics: may decrease the blood glucose-lowering effect.
• Corticosteroids: may decrease the blood sugar levels.
• Angiotensin-converting enzyme (ACE) inhibitors: can enhance blood sugar-lowering effect.
Drug-Food Interactions
• High Sugar Foods: These may counteract the glucose-lowering effect of this tablet.
Drug-Disease Interactions
• Lactic Acidosis: Metformin may precipitate this rare but severe condition; seek immediate medical advice if symptoms appear.
Daily Dosage
• Take this tablet as prescribed by your doctor, based on your condition and response to therapy.
Missed Dose
• If a dose is missed, take it as soon as remembered unless it is near the time for the next dose. Do not double up on doses.
Overdose
• Symptoms of overdose may include nausea, dizziness, and stomach discomfort. Seek prompt medical attention if overdose is suspected.
• Store this tablet in a dry place, away from light and moisture.
• Keep out of reach of children.
• Use before the expiry date.
• Maintain a balanced diet rich in fibre and low in sugars to support blood glucose management.
• Engage in regular physical activity, such as walking or yoga, to improve insulin sensitivity.
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