Nuxvelar 400 Tablet is primarily utilised to manage elevated blood phosphate levels, particularly in patients undergoing dialysis due to severe kidney disease. This medication belongs to a class known as phosphate binders.
Nuxvelar 400 Tablet is prescribed for:
• Managing high phosphate levels in the blood
• Controlling hyperphosphatemia in patients undergoing dialysis due to severe kidney disease
• Lowering the risk of bone disorders associated with elevated phosphate levels
• Reducing chances of vascular calcification caused by increased blood phosphate concentrations
• Mitigating the increased mortality risk resulting from elevated phosphate levels in the bloodstream
• Swallow the tablet whole with a glass of water.
• Take this medicine during or immediately after meals for optimal results.
• Do not crush, chew, or break the tablet.
• Always adhere to the dosage prescribed by your doctor and take it at the same time each day for maximum effectiveness.
• Consult your doctor before making any changes to your medication routine.
Nuxvelar 400 Tablet is taken orally.
The side effects of Nuxvelar 400 Tablet include:
• Nausea
• Vomiting
• Abdominal Pain
• Constipation
• Diarrhoea
Nuxvelar 400 Tablet contains sevelamer (400 mg), which acts in the body by:
• Phosphate Binding: Sevelamer binds with phosphate molecules present in your food within the digestive tract. This binding creates an insoluble complex that is not absorbed by your body and is eventually eliminated through faeces.
• Decreasing Blood Phosphate Levels: By binding with dietary phosphate in your gut, sevelamer reduces the amount of phosphate that enters your bloodstream, effectively lowering blood phosphate levels in patients undergoing dialysis.
Supplementation is required if this medicine is taken by pregnant women as it can reduce the levels of fat-soluble vitamins and folic acid.
Caution is advised.
Avoid alcohol consumption while taking this medication to prevent adverse effects.
Caution is advised.
This medicine is used to manage high phosphate levels in chronic kidney disease patients.
This tablet is unlikely to affect driving or using machines, but ensure you are not experiencing any side effects that could impair such activities.
Avoid using this tablet if you are allergic to sevelamer or any of the tablet's ingredients.
Not recommended below 6 years of age.
Older patients may be more susceptible to side effects. They should take this medication under medical supervision, especially if they have liver or kidney issues or are on other medications.
Drug-Drug Interactions
• Antibiotics: This tablet might decrease the absorption of antibiotics, potentially reducing their effectiveness.
• Thyroid Hormone Medications: Concurrent use of this medicine with thyroid hormone medications may reduce their absorption.
• Immunosuppressants: Using this tablet may lower levels of immunosuppressants, requiring close monitoring.
• Vitamin D Analogues: The absorption of vitamin D analogues might be reduced, influencing calcium metabolism.
Drug-Food Interactions
• High-Phosphate Foods: Consumption of high-phosphate foods can hinder effective control of blood phosphate levels while on this medicine.
Drug-Disease Interactions
• Gastrointestinal Motility Disorders: Patients with conditions affecting the movement of food through the digestive system should exercise caution.
• Bowel Obstruction or Severe Constipation: Patients with these conditions should avoid using this tablet as it may exacerbate symptoms.
Daily Dosage
• The daily dose of this tablet should be taken as directed by your doctor. This dosage may differ based on factors such as the severity of your condition and your response to the medication.
Missed Dose
• If you forget to take a dose of this tablet, take it as soon as you remember. If it is nearly time for your next dose, skip the missed one and continue with your regular schedule. Never increase your dosage without consulting your doctor.
Overdose
• In the event of an overdose, symptoms such as nausea, vomiting, or abdominal discomfort may occur. Do not panic, but inform your doctor about it.
• Store this tablet at a temperature not exceeding 30°C.
• Protect the medicine from light and moisture.
• Do not expose the tablet to extreme heat or cold.
• Always store this medicine out of reach of children.
• Ensure to use the medication before the expiry date printed on the packaging.
• Avoid foods rich in phosphates, such as dairy products, nuts, and beans, to optimise the effectiveness of this tablet.
• Stay well-hydrated unless advised otherwise by your doctor due to dialysis or other medical reasons.
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