Panrux 40 Tablet is primarily used in managing gastroesophageal reflux disease (GERD), particularly in adults with a history of erosive oesophagitis. This medicine is part of the proton pump inhibitors (PPIs) class.
Panrux 40 Tablet is utilised for:
• Managing gastroesophageal reflux disease associated with erosive oesophagitis in adults
• Providing short-term relief (7–10 days) from severe symptoms of GERD
• Aiding the healing process of acid-related oesophageal conditions
• Controlling pathological hypersecretory conditions, including Zollinger-Ellison syndrome in adults
• Swallow the tablet whole with a glass of water.
• Never crush or chew the tablet.
• Always take the recommended dose as directed by your doctor.
• It is crucial not to stop taking this medicine without consulting your doctor first.
Panrux 40 Tablet is taken orally.
The common side effects of Panrux 40 Tablet may include:
• Headache
• Diarrhoea
• Nausea
• Abdominal pain
• Flatulence
Panrux 40 Tablet contains pantoprazole (40 mg), which functions by:
• Proton Pump Inhibition: Pantoprazole blocks the H+/K+-ATPase (proton pump) enzyme system at the secretory surface of gastric parietal cells.
• Reducing Acid Output: By inhibiting proton pumps, pantoprazole decreases stomach acid production, aiding the healing of acid-related gastric and oesophageal lesions.
Should be only used when potential benefit justifies the potential risk to fetus.
Nursing mothers should discontinue breastfeeding if taking this medicine.
Alcohol may reduce the efficacy of the medicine. It is advisable to limit alcohol consumption during treatment.
Contraindicated in patients with moderate or severe liver impairment.
Caution is recommended. Dosage adjustment may be required.
This medicine may cause dizziness. Refrain from driving or operating machinery if you experience dizziness.
Do not take if you are allergic to domperidone or pantoprazole. Inform your doctor of any known allergies.
This medicine is not recommended for children below 18 years of age.
Use with caution in older patients due to increased susceptibility to side effects. Consult your doctor for guidance.
Drug-Drug Interactions
• Medicines dependent on acidic environments: May reduce the absorption of other medicines.
• CYP2C19 metabolised medicines: Potential for increased plasma levels.
• CYP3A4 metabolised medicines: Possible reduction in plasma levels of the co-administered medicines.
Drug-Disease Interactions
• Hypomagnesemia: Long-term use may lead to low magnesium levels.
• Vitamin B12 Deficiency: Prolonged use can result in Vitamin B12 deficiency.
• Bone Fracture Risk: More than one year's use may increase fracture risk.
Daily Dosage
• Take as prescribed by your doctor.
Missed Dose
• If a dose is missed, take it as soon as you remember. If it is nearly time for the next dose, skip the missed dose and continue with the regular schedule.
Overdose
• Symptoms of overdose may include headache, confusion, and nausea.
• Store Panrux 40 Tablet at a cool temperature below 30°C.
• Protect from light exposure.
• Keep out of reach of children.
• Limit intake of spicy foods and caffeine to reduce acid production stimulation.
• Engage in regular exercise to promote digestion and alleviate GERD symptoms.
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