Renorf 500 Tablet is primarily utilised to protect renal health, specifically in conditions such as diabetic kidney disease, paracetamol toxicity, and radiocontrast-induced nephropathy. This combination medication, comprising two active pharmacological agents, belongs to the antioxidant class.
Renorf 500 Tablet is indicated for managing the following conditions:
• Diabetic kidney disease
• Paracetamol poisoning
• Radiocontrast-induced kidney damage
Here are the directions on how to take Renorf 500 Tablet:
• Swallow the tablet whole with a glass of water.
• It can be taken with or without food.
• Avoid crushing, chewing, or breaking the tablet.
• Follow your doctor's prescription precisely.
Renorf 500 Tablet is taken orally.
The side effects of Renorf 500 Tablet may include:
• Nausea
• Vomiting
• Abdominal pain
• Diarrhoea
• Dizziness
Renorf 500 Tablet comprises two active ingredients that collaboratively function as follows:
Acetylcysteine (150 mg):
• Antioxidant Restoration: Acetylcysteine replenishes glutathione levels in the body, a critical antioxidant that safeguards cells from oxidative damage.
• Free Radical Scavenging: Acts as a scavenger of free radicals, minimising oxidative stress.
• Anti-inflammatory and Mucolytic Properties: Demonstrates anti-inflammatory effects and acts as a mucolytic, breaking down mucus in the airways.
Taurine (500 mg):
• Regulation of Cellular Osmolarity: Maintains fluid balance within cells and regulates cellular osmolarity.
• Calcium Homeostasis and Membrane Stabilisation: Modulates calcium homeostasis and stabilises cell membranes.
• Antioxidant Action: Exhibits antioxidant and anti-inflammatory effects, shielding cells from oxidative damage.
These ingredients work synergistically to slow kidney cell damage, enhance kidney function, and avert deterioration in conditions like diabetic kidney disease and paracetamol poisoning.
Exercise caution and consult your doctor before taking the medicine.
Use with care after consulting your doctor to understand the risks and benefits.
Consult your doctor regarding alcohol consumption while on this medication.
Discuss any liver impairments with your doctor before beginning this medication.
Caution is advised for individuals with a history of kidney problems; consult your doctor.
May cause dizziness or fatigue; avoid driving or operating machinery if affected.
Avoid if allergic to acetylcysteine, taurine, or other components; consult your doctor for alternatives.
Primarily for adults; consult a doctor before giving to children under 18 years of age.
More susceptible to side effects; use under medical supervision, especially for individuals above 70 years or with liver or kidney issues.
Drug-Drug Interactions
• Antitussives: May reduce the efficacy of cough suppressants due to the mucolytic action of acetylcysteine.
• Antibiotics: Can interact with certain antibiotics, affecting their effectiveness.
• Activated Charcoal: Decreases the absorption of acetylcysteine, reducing the effectiveness of the medicine.
• Vasodilatory Medicines: Potentiates the hypotensive effect, increasing the risk of low blood pressure.
Drug-Disease Interactions
• Asthma or Bronchospasm: May trigger bronchospasm; use cautiously in patients with these conditions.
• Peptic Ulcer Disease: Potential to exacerbate the condition; exercise caution while taking this medicine.
• Severe Renal Impairment: Use under strict medical supervision due to potential alterations in drug elimination.
Daily Dosage
• Renorf 500 Tablet should be taken as advised by your doctor, considering the severity of your condition and response to therapy.
Missed Dose
• If you miss a dose, take it as soon as you remember.
• If it is almost time for your next dose, skip the missed dose.
• Do not double the dose without consulting your doctor.
Overdose
• Common symptoms of an overdose include nausea, abdominal discomfort, or headaches.
• Seek immediate medical attention if these symptoms occur after an overdose.
• Store at room temperature, ideally below 30°C, in a dry place away from light and moisture.
• Keep out of reach of children.
• Ensure the product is used before the expiry date.
• Maintain a balanced diet with controlled sugar levels if managing diabetic kidney disease.
• Regular blood sugar monitoring is recommended to effectively manage the condition.
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