Clindaren Gel is primarily utilised for the management of mild to moderate acne vulgaris. It is a combination medicine that belongs to the category of topical antibiotics and vitamin B3-based treatments for dermatological conditions.
Clindaren Gel is used for managing the following:
• Mild to moderate acne vulgaris
• Inflammatory acne lesions such as papules and pustules
• Non-inflammatory acne lesions like comedones (whiteheads and blackheads)
• Excessive sebum production in the skin
• Swelling, redness, and tenderness associated with inflammatory acne lesions
• Lightening of post-acne marks and hyperpigmentation
• Ensure your skin is clean and dry before application.
• Apply the product as a gel to the affected areas.
• Gently massage the gel into your skin, avoiding the eyes, mouth, and mucous membranes.
• Wash your hands thoroughly before and after applying the gel.
• Keep the tube tightly closed after use.
• Consult your doctor for specific advice on usage.
Clindaren Gel is applied topically.
The side effects of Clindaren Gel may include:
• Skin dryness, peeling, or flaking
• Redness or irritation at the application site
• Burning or stinging sensation
• Itching
Clindaren Gel contains two active ingredients:
• Clindamycin (1%): This lincosamide antibiotic inhibits bacterial protein synthesis at the ribosomal level, reducing the growth of Propionibacterium acnes bacteria in sebaceous follicles and glands.
• Nicotinamide (4%): Also referred to as vitamin B3, it exerts anti-inflammatory effects when applied topically and regulates sebum production, reducing swelling, redness, and tenderness associated with inflammatory acne lesions while promoting the healing and lightening of post-acne marks.
Exercise caution and consult your doctor before using this medicine if you are pregnant.
Discuss the potential risks and benefits with your doctor before using Clindaren Gel if you are breastfeeding.
No known interactions exist between alcohol and Clindaren Gel, but consult your doctor if you have concerns.
Clindaren Gel is a topical medicine and rarely interacts with liver conditions; however, consult your doctor if you have liver health issues.
This medicine is applied on the skin and seldom interacts with kidney diseases, yet it's advisable to consult your doctor if you have kidney health issues.
Clindaren Gel does not impact your ability to drive or operate machinery.
Clindaren Gel is contraindicated for individuals with known hypersensitivity to clindamycin, lincomycin, nicotinamide, or any other component of the formulation. Consult your doctor before use if you have allergies.
The safety and efficacy of Clindaren Gel in children under 12 years have not been established. Exercise caution and consult your doctor before considering its use in children.
Older patients may use Clindaren Gel under medical supervision, as they may be more susceptible to its side effects.
Drug-Drug Interactions
• Topical Acne Medications: Using Clindaren Gel concurrently with other topical acne medications such as retinoids, benzoyl peroxide, or salicylic acid may cause skin irritation.
Drug-Disease Interactions
• Sunburned or Windburned Skin: Application on sunburned or windburned skin could worsen the condition.
• Inflammatory Bowel Diseases: Individuals with a history of regional enteritis, ulcerative colitis, or antibiotic-associated colitis should avoid Clindaren Gel due to potential exacerbation of symptoms.
• Hypersensitivity: Clindaren Gel is contraindicated for those with known hypersensitivity to clindamycin, lincomycin, nicotinamide, or any other component of the formulation.
Daily Dosage
• Apply Clindaren Gel as prescribed by your doctor. The dosage may vary based on the severity of your acne and your response to the medicine.
Missed Dose
• If you forget to apply Clindaren Gel at the scheduled time, do so as soon as you remember. If it is nearly time for your next application, skip the missed one and return to your regular dosing schedule. Do not apply extra gel to compensate for a missed dose without consulting your doctor.
Overdose
• Symptoms of an overdose may include skin dryness, redness, or irritation at the application site. If these symptoms persist or worsen, inform your doctor.
• Store Clindaren Gel at room temperature, below 25°C.
• Keep it away from extreme heat or freezing conditions, ensuring it is not exposed to direct sunlight or moisture.
• Always keep the tube tightly closed when not in use.
• Keep this medicine out of reach of children for safety reasons.
• Maintain a diet rich in vitamins and minerals, particularly Vitamin B3 (niacin), which aids skin health and can complement the effects of Clindaren Gel.
• Limit your sun exposure, as Clindaren Gel may make your skin more sensitive to sunlight. When outdoors, consider wearing protective clothing and applying a broad-spectrum sunscreen to shield your skin from harmful UV rays.
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